Nude mice bearing Huh7 tumors received an intravenous injection of (i) saline; (ii) Free DOX (5 mg/kg DOX); (iii) DOX/siRNA-L (5 mg/kg DOX, 150 μg/kg siRNA); (iv) Gal-DOX-L (5 mg/kg DOX); (v) Gal-Lipoplexes (150 μg/kg siRNA); or (vi) Gal-DOX/siRNA-L (5 mg/kg DOX, 150 μg/kg siRNA) once a week (n = 4 mice/group), and the tumor size was then monitored for four weeks. Here, GAL is linked to neoplasm.