Previous neuropathologic analysis of autopsies of individual patients carrying the p.A152T MAPT variant have shown different types of abnormal tau accumulation, some fulfilling criteria for corticobasal degeneration, PSP (Kara et al., 2012), or pallidonigroluysian atrophy (Graff-Radford et al., 2013), while others were considered to be unclassifiable tauopathies (Kovacs et al., 2011). The gene discussed is MAPT; the disease is corticobasal degeneration disorder.