FBLN1 and hepatocellular carcinoma: We have shown that the average methylation level across analyzed CpG-sites in cfDNA was associated with higher odds of HCC for VIM (1.48 [1.02, 2.16] for French cases and 2.18 [1.28, 3.72] for Thai cases), and lower odds of HCC for FBLN1 (0.89 [0.76, 1.03] for French cases and 0.75 [0.63, 0.88] for Thai cases) which represents a critical first step in the evaluation of these as potential biomarkers.