PDGFRB and Granuloma: It is noted that nodules of granulomas in different tissues are characterized by the presence of podoplanin-positive cells and lymphatic vessels of heterogeneous and atypical morphology, which frequently express PDGFRβ [42, 48, 49], resembling the podoplanin-labeled cells in the chronically infarcted heart (Fig 6G; 1 month).