Another study revealed that the downstream signalling pathway of Gas6/Axl includes Src, FAK and NF-κB. NF-κB regulates the Gas6/Axl-mediated overexpression of survivin, cyclin D1 and FAK, leading to the proliferation of schwannoma cells, cell-matrix adhesion and enhanced survival.77 The gene discussed is PTK2; the disease is schwannoma.