In the reproductive system, Gas6, Axl and Tyro3 mRNA levels are significantly higher in uterine leiomyoma than in normal uterine myometrium.95, 96 Gas6 expression is evaluated in ovarian tumour tissues and is higher in tumours from patients with residual disease compared with those without residual disease. This evidence concerns the gene GAS6 and Uterine leiomyoma.