It has been reported that CD11b+Ly6G+Ly6Clow G-MDSC is the main MDSC subset to be expanded in tumor animal models.14 Similarly, our data showed that the induction of MDSCs was redirected towards the CD11b+Ly6G+Ly6Clow G-MDSC subset following mTOR signal inhibition, indicating that G-MDSCs had a more important role in improving kidney injury. The gene discussed is ITGAM; the disease is neoplasm.