FOXR2 and Ewing sarcoma: Interestingly, when sorting these tumors out a number of new molecular entities emerged, which could be identified as “CNS neuroblastoma with FOXR2 activation” (CNS NB-FOXR2), “CNS Ewing sarcoma family tumor with CIC alteration” (CNS EFT-CIC), “CNS high-grade neuroepithelial tumor with MN1 alteration” (CNS HGNET-MN1), and “CNS high-grade neuroepithelial tumor with BCOR alteration” (CNS HGNET-BCOR) tumors [28].