The majority of chemokines induced by cationic peptides in mammals are inflammatory chemokines, such as MCP-1 (CCL2), MIP-1α (CCL3), MIP-1β (CCL4), RANTES (CCL5), MCP-3 (CCL7), Gro-α (CXCL1) and IL-8 (CXCL-8), which are produced at high concentrations during infection, suggesting that cationic peptides modulate the inflammatory response induced by diverse pathogens28. This evidence concerns the gene CXCL1 and infection.