BCL2 and cancer: To test this hypothesis, we analyzed cancer genomics data available through cBioPortal (http://www.cbioportal.org) for mRNA expression correlations between PML and DDIT4, BCL2 or TAP1. Our initial analysis of 967 cancer cell lines from the Broad Institute’s Cancer Cell Line Encyclopedia (http://www.broadinstitute.org/ccle)41 showed weak (Spearman’s r = 0.199) but significant (p < 0.01) positive correlation between PML and DDIT4 gene expression (Table 1).