DDIT4 and cancer: Analysis of other available TCGA gene expression data sets for human cancers accessible via the cBioPortal also identified cancers where DDIT4 and PML expression were significantly (p < 0.05) and positively (Spearman’s r = 0.263–0.354) correlated, including breast42, ovarian43, prostate44, colorectal45, kidney46 bladder47 and lung48 cancers (Fig. 7A and B).