However, in four groups of EGb761-treated animals, the expression levels of IL-1β (except for BD + EGb 2 h, all P < 0.01), IL-6 (all P < 0.05), and TNF-α (except for BD + EGb 2 h, all P < 0.05), MCP-1 (except for BD + EGb 2 h, all P < 0.05) and IP-10 (all P < 0.01) significantly reduced as compared to BD group. Here, IL6 is linked to Behcet disease.