PIM1 and neoplasm: 25 proved that miR‐16 and miR‐203 suppressed melanoma cells proliferation in vitro and reduced tumor growth in vivo. Fan et al. 26 demonstrated that miR‐542‐3p is downregulated in melanoma cell lines and clinical tissues, inhibits cell migration, invasion, and epithelial mesenchymal transition (EMT) in vitro, and delays metastasis in vivo via downregulating the proto‐oncogene serine/threonine protein kinase, PIM1.