In addition to conventional clinical lab analysis of lactate dehydrogenase, C-reactive protein (CRP), absolute lymphocyte count (ALC), immune cell repertoire (see flow cytometry), the expression of genes and proteins should be analyzed in serum/plasma for cytokines, chemokines, putative tumor-associated antigens and antibodies at the end of dosing and beyond [14]. The gene discussed is CRP; the disease is neoplasm.