Interleukin (IL)‐32 is documented as pro‐inflammatory cytokine that plays substantial role in various biological processes, whereas the role of IL‐33 has been predictable in various diseases, such as cardiovascular diseases (Miller & Liew, 2011), especially allergic asthma (Liew, 2012; Saluja et al., 2015), allergies, chronic inflammation of the gut (Lopetuso et al., 2013), disorders of the central nervous system (Gadani et al., 2015), and rheumatoid arthritis (Palmer & Gabay, 2011). This evidence concerns the gene IL33 and central nervous system disorder.