IFNG and hepatocellular carcinoma: Although no clear difference of the antigen peptide pool induced IFNγ production was discovered between patients from the two groups, a significantly better antigen peptide pool-specific T cell proliferation (p = 0.037) was observed in the recurrence-free patients (Fig. 5b), indicating that stronger MASCT-induced antigen-specific immune responses may correlate with better clinical outcomes of patients with HCC.