TEK and cystic fibrosis: MS-PPOH also decreased baseline CF in WT mice (from 13.6 ± 0.5 to 10.4 ± 0.8 mL/g; P < 0.05) and in Tie2-CYP2J2 Tr mice (from 14.0 ± 0.6 to 11.7 ± 0.6 mL/g; P < 0.05, Fig 3D).