In response to various stimuli, including allergen and respiratory viruses, IL-6 is considered to be related to tumor progression and angiogenesis.[10] IL-6 may increase IL-4 during Th2 differentiation, inducing inflammation, and it may play as a potential promoting factor for asthma as well as some other lung diseases.[20] Fu et al[21] have reported that overexpression of IL-6 is associated with fixed airflow obstruction, and the highly expressed IL-6 is also found in bronchial epithelial cells of adults and child asthma patients. This evidence concerns the gene IL4 and lung disorder.