The contribution of the TLR variations to thesusceptibility for leprosy has been investigated in different populations, andTLR1, TLR2 and TLR4 variants havebeen reported to be associated with leprosy by previous studies in ethnical differentpopulations such as Indian, Nepalese, African and Brazilian (Johnson et al. 2007, Bochud et al. 2008,2009, Misch et al.2008, Hart & Tapping 2012, Marques et al. 2013). This evidence concerns the gene TLR2 and leprosy.