Next the decreased survival were associated with specimens expressing high levels of H19 than those with low H19 levels by Kaplan–Meier survival curve analysis from primary high grade glioma (WHOIII+GBM) and GBM patients only in TCGA database with full survival data (the Log-Rank test P for HGG < 0.0001 and the Log-Rank test P for GBM = 0.0341) (Fig. 6A). This evidence concerns the gene H19 and glioma.