Lastly, as BAA-induced mechanical antiallodynia in neuropathy is clearly an in vivo indicator of spinal microglial prodynorphin expression and dynorphin A release9, 10, 11, 42, 8 specific GPCR antagonists were intrathecally employed in neuropathic rats to identify the proposed GsPCR responsible for BAA-induced dynorphin A expression. Here, PDYN is linked to neuropathy.