A previous microarray study [18] analysing antibody reactivity to myelin peptides in patients with ADEM and paediatric/adult MS demonstrated distinct profiles of myelin antibody reactivity in these two groups, specifically autoantibodies of the immunoglobulin G (IgG) isotype to MBP and myelin-associated oligodendrocyte basic protein (MOBP) in ADEM patients. Here, MOBP is linked to acute disseminated encephalomyelitis.