NRXN3 encodes a member of the neurexin family of which NRXN1 is associated with Pitt-Hopkins-like syndrome 2 (MIM 614325) [70–72] and ACOT1 is involved in lipid metabolism (Additional file 4: Supplemental text). The gene discussed is NRXN1; the disease is Pitt-Hopkins-like syndrome 2.