TP53 and carcinoma: Intriguingly, the UOK-257 carcinoma cell line (harbouring a mutant p53) showed miR-17-5p expression levels comparable to cancer RCC-Shaw and HCT116 cells, while miR-106b-5p expression levels were comparable to non-cancer HK-2 cells (Fig. 1c and d), a condition similar to that observed in G1-G2 Fuhrman grade patients (where p53 was wild-type though).