By combining the three most suitable markers for the ductal (E-cadherin, EMA and Her2/neu) and lobular (EMA, Her2/neu and EpCAM) subtypes, 100% tumor cell detection was accomplished in 53 out of 58 ductal ovarian metastases and in 7 out of 10 lobular ovarian metastases. This evidence concerns the gene ERBB2 and neoplasm.