Previous study has shown that mitochondrial uptake of ALCAR can supply the cell with acetyl groups that can be utilized for histone acetylation.26 Other studies reported that carnitine has potentiated colon cancer cell death in Caco-2 and SW680 cells42–44 caused by another HDAC inhibitor, sodium butyrate. Here, HDAC9 is linked to malignant colon neoplasm.