A pronounced improvement was observed amongst the mice dosed with 1 mg/kg PEG-IGF-I 3 hrs and 1-day following stroke, on both the gridwalking (F(3,216) = 38.64; P < 0.0001: Fig. 3B) and cylinder tasks (F(3,216) = 16.48; P < 0.0001: Fig. 3E). This evidence concerns the gene IGF1 and Stroke.