However, Umod+/125R and Umod125R/125R mice had a selective defect in renal uric acid handling that was not studied in TgUmodC147W transgenic mice (Bernascone et al., 2010), whereas TgUmodC147W mice had renal cysts, which were not detected in Umod+/125R or Umod125R/125R mice (Table S1). The gene discussed is UMOD; the disease is cystic kidney disease.