COXFA4 and neoplasm: Unexpectedly, real-time PCR assay showed that only NDUFA4, one target among all predicted target genes of miR-7, was significantly downregulated more than five times both in tumor tissue in the p-T-miR-7 injection group (Figure 4E; p < 0.05) and in p-T-miR-7-transfected tumor cells, respectively (Figure 4F; p < 0.05).