Moreover, the colon-formation ability of cells was also impaired unmistakably (Figure 1E; p < 0.05), which was consistent with our previous works.17, 18 To confirm this finding, we also detected the expression of cell-growth-related factors such as CDK2, CDK3, CDK4, and CDK6 in lung cancer cells. Here, CDK4 is linked to lung carcinoma.