Then, to further explore whether downregulation of NDUFA4 contributed to the suppressive effect of TTF-1-promoter-operating miR-7 expression on human lung cancer cells, we transiently co-transfected p-T-miR-7 and p-NDUFA4 into lung cancer cell line 95D cells and observed the possible change on cell growth and metastasis. Here, COXFA4 is linked to lung carcinoma.