MKI67 and prostate adenocarcinoma: Intriguingly, a significant increase was observed in Ki67 immunostaining in both mPIN and prostatic adenocarcinoma lesions in Lzts2LoxP/LoxP-PtenloxP/Wt:PB-Cre4 compound mice when compared to those in PtenloxP/Wt:PB-Cre4 mice (Fig 6C1 and 6C2 versus Fig 6B1 and 6B2).