During this 30-month study, 61 patients (median age: 65 years, IQR, 56.0–78.5 years; men: 39 [63.9%]) who met the Berlin criteria for ARDS and had an initial measurement of NT-proBNP were enrolled (Fig. 1 and Table 1). The gene discussed is NPPB; the disease is acute respiratory distress syndrome.