They demonstrated that elevated FGF-23 was associated more strongly with CHF than with atherosclerotic events (P = 0.02), and uniformly was associated with greater risk of CHF events across subgroups stratified by eGFR, proteinuria, prior heart disease, diabetes, BP control, anemia, LV mass index, and ejection fraction. This evidence concerns the gene FGF23 and congestive heart failure.