FGFR3 and achondroplasia: Achondroplasia (ACH) is an autosomal dominant disorder generally resulting from a specific gain-of-function mutation (G380R) in the fibroblast growth factor receptor 3 (FGFR3) (Wang et al., 2013; Krakow, 2015; Yap and Savarirayan, 2016).