EGR1 and schizophrenia: Interestingly, EGR1 levels in the PFC of schizophrenia patients are positively correlated with the mRNA levels for the glutamic acid decarboxylase 1 (GAD1), whose down-regulation is a robust molecular feature of schizophrenia subjects (Pérez-Santiago et al., 2012; Kimoto et al., 2014).