EGR1 and prostate carcinoma: In order to better characterize how EGR1 binds to its target genes to regulate their transcription, and in an effort to better predict the potential direct EGR1 targets, several studies have investigated EGR1 binding through chromatin immunoprecipitation (ChIP) following by microarray profiling in monocytic differentiation of human monoblastoma cells or following UV-induced apoptosis in prostate carcinoma cells (Arora et al., 2008; Kubosaki et al., 2009).