Furthermore, the chemokine IL-8 (CXCL8), which is associated with Th17 response, was also increased (Figures 3(d) and 3(f)) in individuals with PV, whereas the production of chemokines Th2 and IP-10 (CXCL-10), as well as of the CC chemokine eotaxin-1 (CCL11), was decreased in PV patients in comparison with controls (Figures 3(c) and 3(e), resp). The gene discussed is CXCL10; the disease is acquired polycythemia vera.