In the same way, the IL-12A rs2243115 (Padd = 0.010, Pdom = 0.014, Phet = 0.027, and Pcod1 = 0.024) polymorphism was associated with diminished risk of developing premature CAD (Table 3) under different models adjusted for age, gender, BMI, and current smoking status. This evidence concerns the gene IL12A and coronary artery disorder.