The increased plasma PAF-AH and apoB-PAF-AH activities in patients with H allele of R92H are related to multiple factors including the R92 → H variation, changes in plasma lipoprotein levels, insulin resistance, aging, and gaining weight and thus might be involved in the pathogenesis of PCOS and the increased risks of future cardiovascular diseases in the patients. Here, APOB is linked to polycystic ovary syndrome.