Expression of glycans decorated by α2-3-linked sialic acid (MAA labeling) found here is in accordance with studies showing α2-3-sialylation to be elevated in metastatic colon cancer cell lines.70 α2-3-sialylated glycans are major components of cancer-associated sialyl Lewis antigens which play an important role in E-selectin-mediated cancer cell adhesion to vascular endothelial cells during the course of hematogenous metastasis.71 Thus, influence of hyperglycemia on expression of sialyl Lewis oligosaccharide by MC38 cells must be verified. This evidence concerns the gene SELE and Hyperglycemia.