We found that ~30% of T-ALLs carried a 1–8 gene deletion spanning Pten (Figure 5—figure supplement 2A), a negative regulator of the PI3 kinase and 5–10% of HCCs carried an amplification in Met, a known oncogene in human HCC (Zender et al., 2006). The gene discussed is MET; the disease is hepatocellular carcinoma.