In a recent meta-analysis, Ballestri et al. 44 analyzed a pooled population of 81,411 patients who were followed-up for a median period of 4.5 years, NAFLD was associated with an increased risk of incident MS with a pooled OR of 1.98 for GGT and 1.80 for ALT, respectively. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.