We believe that this phenomenon is akin to the HAbs formation or is closely related to it, and many hitchhikers unidentified and untested as yet may be present in HAbs, including TF-positive ligands of tumor origin such as MUC1 which is overexpressed and aberrantly glycosylated in cancer, and identified as an antigenic component in IgG immune complexes in cancer patients [44, 45]. The gene discussed is TF; the disease is neoplasm.