RBFOX2 and congenital heart disease: RBFOX2 is involved in various diseases and biological processes including congenital heart disease, breast cancer, epithelial-mesenchymal transition and pluripotent stem cell differentiation (Homsy et al., 2015; Braeutigam et al., 2014; Cen et al., 2013; Venables et al., 2013b).