However, the expression of LCK, SERBP1, WIPF1, PFKFB3, RBFOX2, ATF6B, POU6F1 and CA5A in GSE17755 was incompatible with our integrated analysis in RA synovial tissues (Figs. 4A–4E, 4H–4J). The gene discussed is PFKFB3; the disease is rheumatoid arthritis.