MMP9 and colorectal carcinoma: In the same cohort of CRC tissue samples, 71.1 % (64/90) samples with MMP9 overexpression had high expression of Rab1B protein, while 69.7 % (62/89) samples with MMP9 down-regulation also had low expression of Rab1B (P < 0.001, Table 2 and Fig. 2E).