Rab1B, the second Rab1 member, was also found to be increased in cervical cancer [14] and HCC [15], but another study showed that Rab1B protein was down-regulated and inhibited tumor proliferation and migration via regulating TGF-β/Smad pathway in triple-negative breast cancer (TNBC) [16], indicating that Rab1B may have different roles in different cancer types. This evidence concerns the gene RAB1A and hepatocellular carcinoma.