Significantly higher CD105+/PS+/CD41a− EMP counts were observed in AIS patients compared with controls, with three EMP phenotypes (CD105+/CD41a−/CD45− EMPs, CD105+/PS+/CD41a− EMPs and CD105+/CD54+/CD45− EMPs) correlating significantly with brain lesion volume, and CD105+/CD54+/CD45− EMPs showing the strongest correlation. This evidence concerns the gene ENG and androgen insensitivity syndrome.