Focal deletions (Figure 1A, dark blue) of the PARK2 gene were most commonly found in colorectal (21%) and ovarian (25%) carcinomas, while a strikingly high number of tumors, including lung adenocarcinomas, melanomas, bladder, ovarian, and pancreatic, had an overall >40% DNA copy number (DCN) loss of the PARK2 gene (both focal deletion [Figure 1A, dark blue] and as part of whole or part chromosome arm losses [Figure 1A, light blue]). This evidence concerns the gene PRKN and melanoma.