MAP4K4 and lung adenocarcinoma: As shown in Fig. 1C, the rate of MAP4K4 overexpression did not appear to vary among tumors with EGFR mutations (25/32, 78% with MAP4K4 overexpression), KRAS mutations (45/69, 65% with MAP4K4 overexpression), or neither mutation (21/35, 60% with MAP4K4 overexpression), implying that MAP4K4 elevation in lung adenocarcinoma is not associated with KRAS or EGFR mutation, hence excluding mutant KRAS or mutant EGFR as causes for MAP4K4 dysregulation.