Further, we performed an immunohistochemical analysis of CTHRC1 in a tissue microarray containing 101 cervical squamous cell carcinoma tissue samples, 29 cervical adenocarcinoma tissue samples, 19 cervical intraepithelial neoplasia (CIN) and 30 normal cervical tissues. The gene discussed is CTHRC1; the disease is cervical squamous intraepithelial neoplasia.