In the chronic myeloid leukemia model (K562Dox) the following 4 DEPs were found to be involved in the GSH metabolism pathway (G6PD, PRDX2, IDH1 and 6PGD), 3 DEPs in the PPP pathway (G6PD, ALDOC and 6PGD) and 2 DEPs in the glycolysis pathway (ALDOC and PKM2). Here, IDH1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.