Importantly, both the Lin− CD123low and CD127+ populations were increased in the skin of psoriasis patients; however, it is possible that the CD127+ ILC may migrate by a mechanism independent of CXCR4/SDF-1 but CCR6-dependent because high levels of CCR6 were identified in the CD127+ ILC population. The gene discussed is CXCR4; the disease is psoriasis.