TLR2 and infection: These parameters include S+ which can increase as a consequence of TLR2 desensitization caused by a previous influenza virus infection (Didierlaurent et al., 2008), M that may increase as a consequence of previous infectious events (La Gruta et al., 2007; Yin et al., 2013), and the size of the neutrophil pool (Nv) which may decrease by chemotherapy or severe infections (Dick et al., 2008).