ERVW-1 and Hodgkins lymphoma: In addition, we included several samples of lymphomas and endometrial carcinomas in our analysis because of (1) the presence of multinuclear giant Reed-Sternberg cells in Hodgkin lymphomas [36], (2) the detection of full-length ERVWE1 mRNA in endometrial carcinomas [17, 18, 37], and (3) the recently described increased expression of DNA demethylating dioxygenases TET2 and TET3 in seminomas, lymphomas and endometrial carcinomas [30] that could contribute to ERVWE1 transcriptional derepression.