DDIT3 and diffuse large B-cell lymphoma: Diffuse large B cell lymphoma (DLBCL) is a heterogeneous and aggressive lymphoid neoplasm, the treatment of which has significantly improved in the last decade with addition of the anti-CD20 monoclonal antibody rituximab (R) to the chemotherapy regimen consisting of cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisone (R-CHOP) [1].